What can cause infertility in men?

Male infertility has a wide variety of causes, which can be broken down into several major groups:

  • Hormonal problems, such as low levels of testosterone or thyroid hormone.

  • Problems with the testicles, including abnormal growth or development, or damage from trauma and infections.

  • Problems with the flow of sperm within the male reproductive organs, including blocked tubes that transport sperm, genital infections, varicose veins (varicoceles) within the scrotum, or problems with ejaculation.

  • Abnormal sperm function.

  • Inherited or chromosomal disorders, including cystic fibrosis and Klinefelter's syndrome.

  • Exposure to toxins, such as radiation or industrial chemicals.

  • Medications and drugs, including psychiatric medications, alcohol, and anabolic steroids used for bodybuilding.

  • General illnesses, including kidney disease, cirrhosis and malnutrition.

In up to 50% of infertile men, no specific cause can be identified.

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